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Reishi Extract and Inflammation

By Dr. Markho Rafael


For over 2,000 years, Reishi extract has been used as a "cure-all" herbal remedy in Traditional Chinese Medicine, with the oldest written record of any medicinal mushroom in Shen Nong's Herbal Classic. Although it may not be totally accurate to claim that Reishi extract cures everything, traditional as well as modern use indicates that it may be a powerful anti-inflammatory agent in a large host of conditions, including arthritis.

In fact, Chinese medical practitioners have been prescribing Reishi extract for ages in cases of arthritis, bronchitis and other conditions involving any type of inflammation. Modern research in Asia as well as in America and Europe confirm the validity of these uses. Out of 19 papers used for this article, 17 reported positive results in the use or Reishi extract for arthritis. Only two were studies were inconclusive, both of which were conducted by the same research team.

An American study conducted in 1993 by Lin et al. concluded that a water extract of Ganoderma lucidum (Reishi) demonstrated "significant anti-inflammatory activity." A study out of India ten years later found that an extract of Reishi decreased inflammation in conditions of acute edema and chronic edema by 56% and 60%. Seven additional research papers were found during the writing of this article that all concluded that Reishi is a potent anti-inflammatory medicinal mushroom.

Other Reishi studies have been performed which more directly relate to arthritis. A 2006 report by Kenneth Blum et al. provided support that clinical evidence demonstrates the effectiveness and safety of natural substances for joint health, such as glucosamine sulfate , chondroitin sulfate, and Ganoderma lucidum [Reishi].

Also in 2006, a paper by Xi Bao et al. concluded that Reishi in conjunction with another Chinese herbal remedy might exert a beneficial regulation of the immune system effect in patients with rheumatoid arthritis.

Just how Reishi accomplishes its beneficial influence on arthritis may have been stumbled upon by Ho et al. in 2007 when they discovered that GL-PP [Ganoderma lucidum polysaccharide peptide] helped to significantly reduce one of the causative agents of rheumatoid arthritis known as RASF, short for "Rheumatoid Arthritis Synovial Fibroblasts."

A number of other studies also report positive findings for using Reishi extract with arthritis. One of them even reports favorable results in comparing Reishi with prednisone (arthritis drug), and without the side effects. Furthermore, a different study found that supplementation with Reishi extract actually helped to balance the side effects of prednisolone experienced by some patients, including proteinuria and cell toxicity. (Prednisone breaks down in the body to form prednisolone, which is the active compound.)

In conclusion, the majority of research on the use of Reishi extract for inflammation or arthritis appears to support its effectiveness. Please remember that it is very important to always consult a licensed medical doctor before using any herb for medicinal purposes.

Note on name confusion: The name "Reishi" is Japanese for the perennial tree mushroom that American naturalists refer to as "Varnished Conk." In China, it is known as "Ling Zhi." All these names usually refer to the species Ganoderma lucidum, which for the sake of distinction from other types of Reishi may sometimes be called "Common Reishi" or "Red Reishi."

Other related species that are often called "Reishi" include: "Hemlock Reishi" (Ganoderma tsugae)," which is common on hemlock trees in eastern U.S.; the Chinese species known as "Black Reishi" (Ganoderma sinense); another American species found on the west coast which is sometimes referred to as "Red Reishi" (Ganoderma resinaceum), although "Red Reishi" more often refers to G. lucidum in contrast to "Black Reishi," G. sinense; and finally two Japanese species, one that is sometimes known as "Purple Reishi" Ganoderma japonicum, and one without any English name, Ganoderma neo-japonicum.




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